Polycystic Ovarian Syndrome Etiology- Environmental And...

Polycystic Ovarian Syndrome: Etiology- Environmental and Genetic Factors Literature in NFS Seminar 4601 Fall 2015 Ashley Anger Date of Submission: 11/25/15 Introduction: The condition Polycystic ovary syndrome(PCOS) is the most common of endocrine disruptions within women of reproductive ages. The disorder does affect as much as 10% of women within this reproductive lifecycle. The clinical and biochemical features of the condition are diverse and are as follows: fertility disruption, overweight/obesity, irregularities in menstruation (frequent, absent, sporadic) insulin resistance/type 2 diabetes, and increased risk of cardiovascular disease (Jeanes Hart Smith Barr, 2009). The exact aetiology of Polycystic ovary syndrome (PCOS) is unknown but does involve both environmental influencers and genetic factors. In summery Polycystic ovary syndrome (PCOS) is a common endocrine condition associated with metabolic dysfunction, infertility, and hyperandrogenism. Treatment for PCOS includes diet and lifestyle changes in order to promote a healthy body mass index (BMI) and further reduce hyperinsulinaemia (a symptom of the condition). Medications such as metfo rmin/Glucophage might be utilized for management of the presenting symptoms. PCOS symptoms at present-day can only be managed and no cure for Polycystic ovary syndrome available. (Jeanes Hart Smith Barr, 2009). Diet: Proper diet/nutrition and weight loss can help sufferers of PCOS and aid inShow MoreRelatedWhat Are Polycystic Ovarian Syndrome ( Pcos ) Is The Most Common Endocrine Disorder?3279 Words   |  14 PagesAbstract Polycystic ovarian syndrome (PCOS) is the most common endocrine disorder diagnosed in women of reproductive age. The disease manifests itself with varying symptoms and has long term consequences of heart disease, diabetes, and infertility. PCOS has no clear etiology or pathophysiology, and as new information is being contributed, the mechanism and components of the disease is being updated. Presented here are the most understood and accepted components of PCOS, and its pathology as a reproductiveRead MoreThe Pathophysiology Behind Pcos : Inflammation1681 Words   |  7 PagesReview Alexandra Bailin Abstract, REFS Purpose of review Recent findings Summary Introduction Polycystic ovary syndrome (PCOS) is the most common endocrine disorder among reproductive aged women, with a prevalence of 16.6-18% according to the 2003 Rotterdam criteria (1-3). Though PCOS is extremely common, up to 70% of women with the syndrome are undiagnosed (3). The PCOS diagnosis is one of ovarian dysfunction and hyperandrogenism, and as such has important implications for reproductive healthRead MoreThe Role Of Polycystic Ovary Syndrome ( Pcos )2046 Words   |  9 PagesEPIDEMIOLOGY Polycystic Ovary Syndrome (PCOS) is a common endocrine disorder that affects 4% to 12% of women of childbearing age.1 The proportion of individuals in a population with PCOS depends on the diagnostic criteria.2 According to the criteria implemented by the European Society for Human Reproduction and Embryology/American Society for Reproductive Medicine, PCOS is as great as 15% to 20%.2 As stated in The National Institute of Health Office of Disease Prevention Report, PCOS impacts aboutRead MoreType 2 Diabetes Mellitus As A Slow Progressive Disease1358 Words   |  6 Pagespigmentations, known as acanthosis nigricans (Mahan et al., 2012). Developing Type 2 Diabetes Mellitus is multi-factorial and involves several risk factors; some of the most powerful contributing risk factors are adiposity and a longer duration of obesity (Mahan et al., 2012). Others risk factors are multi-factorial and they include genetic and environmental factors, including a family history of diabetes; older age; obesity, particularly intraabdominal obesity; physical inactivity; excessive intake of calories;Read MoreA New Day It s A Blessing2392 Words   |  10 Pagesand morbidity and mortality: diabetes is the seventh leading cause of death in the US. It is the leading cause of kidney failure, neuropathy, non-traumatic amputations, and blindness in adults. In addition, diabetes is considered to be a major risk factor for the development of cardiovascular disease and stroke. Classification Diabetes divided into different types according to it cause. For people who have a pancreas that does not genetically produce insulin hormone during childhood theyRead MoreThe Patient With Diabetes Mellitus2294 Words   |  10 Pagesmonitoring systems †¢ Insulin analogues and hormones such as insulin degludec and pramlintide respectively (Atkinson, Eisenbarth Michels, 2014) †¢ Cell-based tolerogenic therapy (Van Belle, Coppieters Herrath, 2011) †¢ ÃŽ ²-cell replacement †¢ Avoid environmental triggers such as cow milk or wheat protein (Van Belle, Coppieters Herrath, 2011) Type 2 Pathophysiology Treatment †¢ Chronic fuel surfeit – lack of compensation for fuel surfeit by the islet ÃŽ ² cells (Nolan, Damm Prentki, 2011). †¢ Metabolic